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Prevotella intermediaおよびPrevotella nigrescens由来溶血毒素に関する研究 Study on the hemolysin from Prevotella intermedia and Prevotella nigrescens ja ja 鎌口, 有秀 中村, 麗子 岡本, 公彰 馬場, 久衛 hemolysin Prevotella intermedia Prevotella nigrescens P(論文) Hemolysin genes of Prevotella intermedia that have been reported were not detected by PCR in many strains of P. intermedia and Prevotella nigrescens. In both organisms, hemolytic activity was observed in many strains which had not retained the hemolysin genes. Hemolysin was partially purified from the outer membranes of P. intermedia and P. nigrescens. This hemolysin was activated with SH reagents and inhibited with SH blockers. After heating at 100℃ for 10 minutes, the hemolytic activity was almost inhibited, but heat stable hemolysin was also observed. Therefore, it is suggested that P. intermedia and P. nigrescens have two different hemolysins on the outer membrane which are related to growth in the oral cavity. 2004-06 jpn departmental bulletin paper https://hsuh.repo.nii.ac.jp/records/8876 AN0008135X 東日本歯学雑誌 23 1 43 52 https://hsuh.repo.nii.ac.jp/record/8876/files/KJ00004266356.pdf application/pdf 891.9 kB 2004-06-01