2026-03-15T20:37:07Z https://hsuh.repo.nii.ac.jp/oai

oai:hsuh.repo.nii.ac.jp:02000576 2025-11-05T06:06:13Z 157:1761616112340

Self−inflicted Traumatic Ulcerative Granuloma with Stromal Eosinophilia :A Case Report with Psychological Implications Tetsuro, MORIKAWA Koki, YOSHIDA Dedy, ARIWANSA Masafumi, UTSUNOMIYA Yasuhito, MINAMIDA Fumiya, HARADA Jun, SATO Hirofumi, MATSUOKA Hisashi, OOI Renata, CHAŁAS Eiji, NAKAYAMA Hiroki, NAGAYASU Yoshihiro, ABIKO open access Traumatic ulcerative granuloma with stromal eosinophilia Eosinophils Self−injurious behavior Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a rare, benign, self−limiting oral mucosal disease. In adults, TUGSE is thought to be caused by trauma from fractured teeth or ill−fitting dental prostheses, although its exact cause remains unknown. Its histological hallmark is diffuse infiltration of granulation of tissue and inflammatory cells with increased capillary vascularity beneath the ulcerated mucosa. The presence of eosinophils has been well−documented in previous reports. TUGSE often resembles squamous cell carcinoma and may arise from self−injury linked to psychological problems. The patient reported here was a 65−year−old female who visited our hospital with ulceration in the left upper gingival area extending to the buccal mucosa. Ulceration occurred after the extraction of her left maxillary molar 6 months before presentation ; she had visited several oral surgeons but did not receive satisfactory treatment. She had repeatedly pricked the extraction socket and its surrounding area with a needle, believing that this was the best treatment to remove ‘unhealthy blood’ from the lesion. This case of TUGSE was caused by self−injury, possibly accompanied by psychological problems. When adults encounter TUGSE, detailed medical interviews and psychological interventions may be crucial. 2025-06-30 eng departmental bulletin paper VoR https://hsuh.repo.nii.ac.jp/records/2000576 18805892 北海道医療大学歯学雑誌 The Dental Journal of Health Sciences University of Hokkaido 44 1 63 66 https://hsuh.repo.nii.ac.jp/record/2000576/files/dj-hsuh_44-1_13.pdf application/pdf 11.2 MB