{"created":"2023-05-15T11:30:49.248509+00:00","id":6694,"links":{},"metadata":{"_buckets":{"deposit":"295ff281-da2d-4140-aad8-5b43e83d0820"},"_deposit":{"created_by":17,"id":"6694","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"6694"},"status":"published"},"_oai":{"id":"oai:hsuh.repo.nii.ac.jp:00006694","sets":["89:516"]},"author_link":["20397","34592","35342","35343"],"item_1693191265938":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_2_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1982-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"61","bibliographicPageStart":"53","bibliographicVolumeNumber":"1","bibliographic_titles":[{"bibliographic_title":"東日本歯学雑誌","bibliographic_titleLang":"ja"}]}]},"item_2_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"南出, 千景","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"20397","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡田, 泰紀","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"34592","nameIdentifierScheme":"WEKO"}]}]},"item_2_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MINAMIDE, Chikage","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"35342","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"OKADA, Yasunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"35343","nameIdentifierScheme":"WEKO"}]}]},"item_2_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_2_description_11":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"細胞内コラーゲン原線維の検索のためにコットン・ペレット法を用いてラット背部に肉芽腫を発症させ電子顕微鏡を用いて観察をおこなった。その結果,細胞の小体内にコラーゲン原線維が認められるものが存在した。細胞内コラーゲン原線維は,その形態から2つのタイプが観察された。その1つは,コラーゲン原線維を含む小体内部が明調で,コラーゲン原線維の横紋構造が明らかに認められるもの。もう1つのタイプは,小体内が暗調で,コラーゲン原線維の横紋構造が不明瞭か,もしくは認められないもの。これらの所見は,細胞により取り込まれ,細胞内で消化をうける一連の過程で生じるものと思われ,またコラーゲン原線維を含む細胞は,その細胞小器官の検索から,特徴的な線維芽細胞の形態を備えていた。以上のことから,線維芽細胞の機能は,コラーゲン合成のみならず,コラーゲン線維の崩壊にも役割をはたしていることが示唆される。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_2_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Intracellular collagen fibrils were detected by electron microscopy in experimental granulomas induced in the back of rats by cotton pellets. The banded intracellular collagen fibrils were ob-served in phagocytic vacuoles. Two types of collagen fibril-containing vacuoles were seen. In one type the vacuoles contained an electron-lucent material and the periodicity of the collagen fibrils was clearly seen. In the other type, the vacuoles contained an electron dense matrix and collagen fibrils were frequently not clearly evident. The cells that contained collagen fibrils had the features characteristic of fibroblasts actively engaged in collagen synthesis. These results suggest that these intracellular collagen fibrils had been phagocytosed by fibroblasts. It is proposed that fibroblasts have the ability not only for the biosynthesis of collagen, but also for the phagocytosis of collagen fibrils during the rapid remodelling of connective tissue.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_2_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN0008135X","subitem_source_identifier_type":"NCID"}]},"item_2_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Operative Dentistry, School of Dentistry, HIGASHI-NIPPON-GAKUEN UNIVERSITY"}]},"item_2_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"東日本学園大学歯学部歯科保存学第二講座"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"1982-12-31"}],"displaytype":"detail","filename":"KJ00000094305.pdf","filesize":[{"value":"3.2 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"<Original>Electron Microscopic Observations on Intracellular Collagen Fibrils in Cotton Pellet-induced Granulomas","objectType":"fulltext","url":"https://hsuh.repo.nii.ac.jp/record/6694/files/KJ00000094305.pdf"},"version_id":"dd18b2cb-1388-448f-8a6c-ba7d05f3ed0a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cotton pellet granuloma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intracellular collagen fibrils","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fibroblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"<Original>Electron Microscopic Observations on Intracellular Collagen Fibrils in Cotton Pellet-induced Granulomas","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"<Original>Electron Microscopic Observations on Intracellular Collagen Fibrils in Cotton Pellet-induced Granulomas","subitem_title_language":"en"},{"subitem_title":"<原著>コットン・ペレット肉芽腫において見られた細胞内コラーゲン原線維の電子顕微鏡的観察","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"17","path":["516"],"pubdate":{"attribute_name":"PubDate","attribute_value":"1982-12-31"},"publish_date":"1982-12-31","publish_status":"0","recid":"6694","relation_version_is_last":true,"title":["<Original>Electron Microscopic Observations on Intracellular Collagen Fibrils in Cotton Pellet-induced Granulomas"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-12-21T06:40:56.645164+00:00"}