@article{oai:hsuh.repo.nii.ac.jp:00007164,
 author = {賀来, 亨 and 舘山, 美樹 and 奥山, 富三 and 岩井, 正行 and 新保, 亮一 and 鍔原, 茂 and 有坂, 一男},
 issue = {2},
 journal = {東日本歯学雑誌},
 month = {Dec},
 note = {P(論文), Forty-two cases of oral squamous cell carcinomas were studied by the immunoperoxidase technique (avidin-biotin peroxidase complex method) to determine the presence of Epithelial Membrane Antigen (EMA) using an EMA monoclonal antibody. The tissues employed were formalin-fixed and paraffin-embedded. 31 out of 42 squamous cell carcinomas showed positive reaction in the presence of EMA. In most of the cases staining was patchy. There was a tendency for EMA to be present in the better differentiated zones and there was a definite correlation with the degree of differentiation of squamous cell carcinomas. Normal squamous epithelium showed negative for EMA. Nondysplastic squamous epithelium adjacent to positive squamous cell carcinoma frequently showed positive staining, which however was confined to the superficial layers. Dysplastic epithelium showed staining confined to the superficial layer and cytoplasmic staining was also weaker. It was confirmed by evidence in the present report that EMA is a valuable marker for the initial change of malignant transformation in oral mucosa.},
 pages = {169--178},
 title = {<原著>口腔扁平上皮癌におけるEpithelial Membrane Antigenの局在に関する免疫組織化学的研究},
 volume = {3},
 year = {1984}
}