@article{oai:hsuh.repo.nii.ac.jp:00007851, author = {後藤, 邦彦}, issue = {1}, journal = {東日本歯学雑誌}, month = {Jun}, note = {P(論文), The healing processes of mandibular fractures in rats with intraperitoneal administration of inorganic tin chloride solution was examined by ^<99m>Tc scintigraphy, microradiography, X-ray radiography, and histological examinations. Seventy-five Wistar rats, aged 8 weeks and weighing about 200 g at the start of the experiment, were used. The rats were separated into three groups : group I (32 rats), mandibular fractured, and administered inorganic tin chloride solution, grop II (32 rats), mandibular fracture only: grop III (3 rats), untreated. Rats in group I receieved an intraperitoneal injection of inorganic tin chloride solution every three days before sacrifice. The observation stook place 4, 7, 14, 21, 28, 35, 42, and 49 days after the start of the experiment. The bone scitigrams obtained from the rat mandibles with fractures showed well defined uptake of ^<99m>Tc, corresponding to the fractured lesions. The X-ray radiograms and microradiogrames clearly showed the healing process of the bone fractures in detail. The histological findings supported these results. The healing processes of bone fractures in group I, fractures with administration of inorganic tin chloride solution, was slower than that of rats in group II, fractures only. In conclusion, the healing process of bone fractures was disturbed by the administration of inorganic tin chloride solution and this was also confirmed by the radiological and the histological observation.}, pages = {49--69}, title = {塩化第一錫投与によるラット顎骨骨折治癒過程の変化 : 放射線学的観察を中心に}, volume = {12}, year = {1993} }