{"created":"2023-05-15T11:31:57.190402+00:00","id":8220,"links":{},"metadata":{"_buckets":{"deposit":"17dca287-b82d-404d-8448-1046058ec37b"},"_deposit":{"created_by":17,"id":"8220","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"8220"},"status":"published"},"_oai":{"id":"oai:hsuh.repo.nii.ac.jp:00008220","sets":["89:575"]},"author_link":["24891","36895","36896"],"item_1693191265938":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"VoR"}]},"item_2_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-12-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"147","bibliographicPageStart":"133","bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"東日本歯学雑誌","bibliographic_titleLang":"ja"}]}]},"item_2_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"沓澤, 政幸","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"24891","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小鷲, 悠典","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"36895","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"久保木, 芳徳","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"36896","nameIdentifierScheme":"WEKO"}]}]},"item_2_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_2_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"The purpose of this study was to evalute the pathological changes of the penodontal disease by measurement of total protein, matrix metalloproteinase (MMP)-8, interleukm (IL)-1 β and granulocyte macrophage colony-stimulating factor (GM-CSF) in the gingival crevicular fluid (GCF). A total of 157 sites were used in the experiment (124 sites with adult penodontitis and 33 sites with healthy penodontal tissue). The measurement of total protein in GCF was performed by Bradford method. The determination of MMP-8 in GCF was performed by the EIA system. The measurements of IL-1 β and GM-CSF were used by the ELISA systems. The flow of GCF, gingival index (GI), gingival bleeding index (GBI) and probing depth were examined as clinical parameters. The compositions of amino acid in GCF were analyzed by the ammo acid analysis. The results were as follows 1 There were close correlations among the inflammation indices (flow of GCF, GI and GBI) and the amounts of total protein, IL-1 β and MMP-8 in GCF. 2 The content of GM-CSF in GCF was not detected by this ELISA system (<7 6pg). 3 By the ammo acid analysis of GCF, the content of hydroxyprolm was less than the experimental error (0 001<residue/1000residues). 4 The rose-diagram of ammo acids in GCF characterised the status of the penodontal diseese. Thease results suggested that the measurements of total protein, IL-1 β and MMP-8 in GCF were useful for the diagnosis of the penodontal disease activity and the ammo acids analysis of GCF might characterize the pathological changes of the periodontal disease.","subitem_description_type":"Other"}]},"item_2_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN0008135X","subitem_source_identifier_type":"NCID"}]},"item_2_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Penodontology and Endodontology, School of Dentistry, Health Sciences University of Hokkaido/Department of Biochemistry, Hokkaido University School of Dentistry"}]},"item_2_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"北海道医療大学歯学部"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"1996-12-31"}],"displaytype":"detail","filename":"KJ00000095490.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"<原著>歯肉溝滲出液による成人性歯周炎の病勢診断","objectType":"fulltext","url":"https://hsuh.repo.nii.ac.jp/record/8220/files/KJ00000095490.pdf"},"version_id":"5d2d9b0e-003d-45c9-b8ba-cf0a28a652f6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gingival crevicular fluid (GCF)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"matrix metalloprotemase (MMP)-8","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"interleukm (IL)-1 β","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"granulocyte macrophage colony-stimulating factor (GM-CSF)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"amino acid analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"<原著>歯肉溝滲出液による成人性歯周炎の病勢診断","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"<原著>歯肉溝滲出液による成人性歯周炎の病勢診断","subitem_title_language":"ja"},{"subitem_title":"<ORIGINAL ARTICLE>Diagnosis of disease activity of adult periodontitis by gingival crevicular fluid","subitem_title_language":"en"}]},"item_type_id":"2","owner":"17","path":["575"],"pubdate":{"attribute_name":"PubDate","attribute_value":"1996-12-31"},"publish_date":"1996-12-31","publish_status":"0","recid":"8220","relation_version_is_last":true,"title":["<原著>歯肉溝滲出液による成人性歯周炎の病勢診断"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2024-02-08T07:35:29.319517+00:00"}