@article{oai:hsuh.repo.nii.ac.jp:00008337, author = {細川, 洋一郎 and 金子, 昌幸 and 安河内, 太郎}, issue = {1}, journal = {東日本歯学雑誌}, month = {Jun}, note = {P(論文), This paper reviews trials of combined chemotherapy and radiotherapy (with or without surgery) of head and neck cancer. The trials allow the following conclusions : 1 Adjuvant chemotherapy reduced distant metastasis, but did not improve survival. 2 Pilots trials of neoadjuvant chemotherapy showed a high tumor response rate, but did not improve survival in the long term. 3 Neoadjuvant chemotherapy increased an organ preservation rates in some randomized trials. 4 This possible to improve local control and survival by concomitant chemotherapy although toxicity makes this procedure debatable.}, pages = {1--13}, title = {<総説>頭頸部癌における併用化学療法の現状}, volume = {17}, year = {1998} }