@article{oai:hsuh.repo.nii.ac.jp:00008342,
 author = {石井, 久淑 and 太田, 勲 and 山根, 美子 and 猪股, 孝四郎},
 issue = {1},
 journal = {東日本歯学雑誌},
 month = {Jun},
 note = {P(論文), 骨格筋線維は種々な要因により肥大したり,萎縮したりすることが知られている。例えば,適度な運動負荷は筋線維を肥大させ,除神経あるいは筋の不動化は筋線維を萎縮させる。筋線維の肥大あるいは萎縮の程度を評価するために,つぎのような指標が用いられている。(1)筋線維の横断面積,(2)筋線維の横断面の短径と長径の平均値,(3)筋線維の短径である。しかし,これらは主として四肢筋について用いられている指標である。顎顔面あるいは口腔領域に存在する骨格筋に関する指標については,十分に検討されていない。本論文は,咀嚼筋の肥大あるいは萎縮を評価するための簡便で,しかも妥当な指標について検討した。, This study investigated the appropriate indexes for evaluation of hypertrophy or atrophy in masticatory muscles of the rat. Masseter muscle of Wistar male rats was used in the study. The muscle was excised under anesthesia with pentobarbital and quickly frozen in isopentane cooled with liquid nitrogen. Serial cross sections (10μm in thickness) of the middle portion of the muscle was cut on a cryostat microtome at -25℃. The cross sections were cut at nearly right angles and at an oblique angle (about 45°) with the long axis of the muscles. These sections were stained with NADH-TR. The cross sectional area (CSA) and the short diameter of the muscle fibers were measured with an Image Processing and Analysis System (Quantimet 600). There were no significant differences in the short diameter of the fibers sectioned at right angles and at oblique angles. The CSA of the muscle fibers sectioned obliquely was 15% larger than that at the nearly right angles. This difference was statistically significant. The results indicate that the short diameter of muscle fibers may be used as an index to evaluate muscle hypertrophy and atrophy.},
 pages = {61--65},
 title = {<原著>ラット咀嚼筋線維の肥大あるいは萎縮を評価する指標について},
 volume = {17},
 year = {1998}
}