{"created":"2023-05-15T11:32:18.637805+00:00","id":8710,"links":{},"metadata":{"_buckets":{"deposit":"6dca2e4b-5df2-4dc2-887e-be9a0fb5cbd3"},"_deposit":{"created_by":17,"id":"8710","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"8710"},"status":"published"},"_oai":{"id":"oai:hsuh.repo.nii.ac.jp:00008710","sets":["89:570"]},"author_link":["26321","37271","37272"],"item_2_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"10","bibliographicPageStart":"1","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"東日本歯学雑誌","bibliographic_titleLang":"ja"}]}]},"item_2_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"武田, 正子","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"26321","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"内田, 暢彦","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"37271","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 裕子","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"37272","nameIdentifierScheme":"WEKO"}]}]},"item_2_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_2_description_12":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_description":"Sectioning of glossopharyngeal nerves which innervate the taste buds in the circumvallate papillae caused apoptosis of taste buds, the numbers decreasing and the taste buds disappearing after 11 days. This indicates that gustatory nerves may release a trophic substance that induces and maintains taste buds. Taste bud cells contain neurotrophins, NCAM, NSE, PGP9.5, and NeuroD which are specific markers of neurons. The BDNF and GDNF of neurotrophins, and Trk B and GFRαl of their receptors were expressed in normal taste bud cells. After denervation they were still expressed in the remaining taste bud cells, and after regeneration of nerves they reappeared in regenerated taste bud cells. It is suggested that BDNF and GDNF are involved in ensuring an adequate contact between taste bud cells and nerves, and that they act as a neurotrophic factor for innervating gustatory neurons, although they can not prevent apoptosis of taste bud cells. The types of taste bud cells containing NCAM, NSE, PGP 9.5, serotonin, Mash 1, and Neuro D are also discussed.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_2_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN0008135X","subitem_source_identifier_type":"NCID"}]},"item_2_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Oral Anatomy, Health Sciences University of Hokkaido/Department of Oral Surgery School of Dentistry, Health Sciences University of Hokkaido"}]},"item_2_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"北海道医療大学歯学部口腔解剖学第二講座/北海道医療大学歯学部口腔外科学第一講座"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2002-06-30"}],"displaytype":"detail","filename":"KJ00000095982.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"<総説>味蕾細胞と神経","objectType":"fulltext","url":"https://hsuh.repo.nii.ac.jp/record/8710/files/KJ00000095982.pdf"},"version_id":"312e7276-3218-447e-9b2d-441ba8a81d66"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Taste bud","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Apoptosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Denervation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"BDNF","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"GDNF","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"<総説>味蕾細胞と神経","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"<総説>味蕾細胞と神経","subitem_title_language":"ja"},{"subitem_title":"<REVIEW>Taste bud cells and nerves","subitem_title_language":"en"}]},"item_type_id":"2","owner":"17","path":["570"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2002-06-30"},"publish_date":"2002-06-30","publish_status":"0","recid":"8710","relation_version_is_last":true,"title":["<総説>味蕾細胞と神経"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2024-02-27T23:59:24.024045+00:00"}