@article{oai:hsuh.repo.nii.ac.jp:00008794,
 author = {大桶, 華子 and 工藤, 勝 and 加藤, 元康 and 河合, 拓郎 and 國分, 正廣 and 新家, 昇},
 issue = {2},
 journal = {東日本歯学雑誌},
 month = {Dec},
 note = {P(論文), To provide a painless and comfortable dental treatment, the effects of thinner disposable dental injection needles and Nitrous oxide (N_2O) and oxygen inhalation, conscious sedation for pain relief at puncture in the oral mucosa were compared. Volunteers had the oral mucosa punctured by 31G (φ0.28mm) or 33G (φ0.26mm) dental needles at pre-inhalation, post 30% N_2O inhalation, and post 50% N_2O inhalation. The pain was evaluated by VAS and the state-anxiety by FAS. Systolic and diastolic blood pressures (SBP, DBP), and heart rate (HR) were measured. The VAS points at 30% and 50% N_2O inhalation were significantly lower than at pre-inhalation (p < 0.05), however there was no significant difference between 31G and 33G (Fig. 2). From the FAS score, SBP, DBP, and HR, there were no significant differences between pre-inhalation and post-inhalation or 31G and 33G (Fig. 3, Fig. 4). In both groups with 50% N_2O, some cases had stoppage of inhalation, because of complaints of discomfort. In conclusion, there were no significant differences in pain, state-anxiety, and change in cardiovascular system with 31G and 33G, whereas pain was lowed by N_2O inhalation. These results indicate that N_2O inhalation sedation is more effectively to alleviate pain in the puncture of the oral mucosa than thinner disposable dental needles.},
 pages = {261--266},
 title = {<原著>極細歯科用ディスポーザブル注射針と笑気吸入鎮静法が口腔粘膜刺入の疼痛緩和に及ぼす影響},
 volume = {21},
 year = {2002}
}