Purpose: Epidemiological analysis of suicide in Sapporo City in these about thirty years. Materials and Methods: The number of suicide and population depend on vital statistics and population census, respectively. The source of standard mortality ratio (SMR) is the series of" SMR of main diseases in Hokkaido". Unemployment rates depend on Labour Force Survey. Causes and measures of suicide depend on the data of the National Police Agency. These data are analysed, being classified by sex or age. Results: From 1980 to 2010, the crude death rate of suicide in Sapporo City was not significantly high (P>0.05), though in several years it was significantly low (P<0.05). There was a tendency that the SMR became gradually high from 1982 to 2009. There was a high correlation between the crude death rate of suicide in Sapporo City and the unemployment rate (r=0.87, P<0.01). When the unemployment rate decreases by 1%, about 70 suicides will be avoided. The crude death rate of suicide based on "health problems" was significantly low in Sapporo City (P<0.05). Discussion: Though the crude death rate of suicide is not prominently high in Sapporo City, we should be careful about the increase in its SMR. Improvement in the condition of economy is one of the most effective measures to decrease suicides.