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<原著>ラット耳下腺細胞のアミラーゼ分泌反応とサイクリックAMP生成に対するCa^<2+>およびEGTAの効果
https://hsuh.repo.nii.ac.jp/records/7433
https://hsuh.repo.nii.ac.jp/records/743344851661-5ed1-4372-886d-77b5b29948a3
名前 / ファイル | ライセンス | アクション |
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<原著>ラット耳下腺細胞のアミラーゼ分泌反応とサイクリックAMP生成に対するCa^<2+>およびEGTAの効果 (455.8 kB)
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
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公開日 | 1988-12-31 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | <原著>ラット耳下腺細胞のアミラーゼ分泌反応とサイクリックAMP生成に対するCa^<2+>およびEGTAの効果 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | <ORIGINAL ARTICLE>Effect of Ca^<2+> and EGTA on amylase secretion and cyclic AMP accumulation in rat parotid cells | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | parotid glands | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | amylase | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Ca | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | EGTA | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cyclic AMP | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ページ属性 | ||||||
内容記述タイプ | Other | |||||
内容記述 | P(論文) | |||||
言語 | ja | |||||
著者名(日) |
相良, りか子
× 相良, りか子× 松井, 聡子× 東城, 庸介× 松本, 仁人 |
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著者所属(日) | ||||||
ja | ||||||
東日本学園大学歯学部歯科薬理学講座 | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Dental Pharmacology, School of Dentistry, HIGASHI-NIPPON-GAKUEN UNIVERSITY | ||||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | The effects of Ca^<2+> and EGTA on rat parotid amylase secretion and cyclic AMP accumulation were investigated in vitro using a dispersed acinar cell preparation. Amylase secretion induced by isoproterenol and dibutyryl cyclic AMP was significantly enhanced by pre-treatment (30min) with more than 50μM Ca^<2+>. Depletion of intracellular Ca^<2+> by pre-treatment with 2mM EGTA reduced the amylase secretion, although the pre-treatment was unable to completely block the secretion. The pre-treatment with Ca^<2+> and EGTA did not alter the rise in cellular cyclic AMP induced by isoproterenol. These results suggest that intracellular Ca^<2+> is necessary to elicit the maximum amylase secretion and that Ca^<2+> may be involved in the exocytosis of parotid amylase at steps distal from the cyclic AMP metabolism. | |||||
言語 | en | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN0008135X | |||||
書誌情報 |
ja : 東日本歯学雑誌 巻 7, 号 2, p. 67-72, 発行日 1988-12-31 |
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出版タイプ | ||||||
出版タイプ | VoR |