| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2024-04-10 |
| タイトル |
|
|
タイトル |
骨・歯に由来する加工移植材の創成とラット生体内での特性評価 |
|
言語 |
ja |
| タイトル |
|
|
タイトル |
Creation of bone- and tooth-derived graft materials and their characteristic evaluation in rats |
|
言語 |
en |
| 言語 |
|
|
言語 |
jpn |
| 著者 |
横関, 健治
根津, 尚史
志茂, 剛
村田, 勝
|
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Perforation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Ultrasonic Demineralized |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
surface area |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Bone defects in the oral region such as the alveolar bone and jawbone often require hard tissue regeneration from the viewpoint of oral system function recovery, and local bone regeneration is a major issue in the dental field. In clinical practice, it is common for compact bone plate to be used for transplantation to be immediately transplanted with freshly perforated autogenous bone. Therefore, we focused on ultrasonic demineralization as a rapid demineralization of perforated bone and further processing inside the bone. In this experiment, adult rat parietal bone−derived compact bone was subjected to physicochemical processing, that is, treatment with mechanical perforation and ultrasonic demineralization by 2% nitric acid. The purpose of this experiment is to observe the ultrastructure of four types of processed bones ( FBP group, DFBP group, UFBP group, UDFBP group) with a scanning electron microscope and to observe bone and cartilage induction phenomena in the subcutaneous tissue of the back of the rat after 4 weeks. Observation of the surface before implantation by SEM revealed a fibrous structure that appeared to be acid−insoluble collagen in DFBP and UDFBP. Focusing on the P and Ca elements present on the surface, DFBP and UDFBP were reduced to about 1/10 or less of FBP and UFBP. The processing of perforated plate−shaped compact bone (ultrasonic nitric acid demineralization) results in a structural change that allows cells and blood vessels to penetrate by the formation and expansion of cracks in the bone matrix. This is thought to have contributed to the osteoinduction of the space. |
|
言語 |
en |
| 書誌情報 |
ja : 北海道医療大学歯学雑誌
en : The Dental Journal of Health Sciences University of Hokkaido
巻 42,
号 2,
p. 21-35,
発行日 2023-12-31
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
18805892 |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
骨・歯に由来する加工移植材の創成とラット生体内での特性評価
