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<原著>耳下腺アミラーゼ活性の周期性変化におよぼす急性ストレプトゾトシン糖尿病の作用について
https://hsuh.repo.nii.ac.jp/records/7126
https://hsuh.repo.nii.ac.jp/records/71261ba88a76-3508-465e-b3df-30ab31e1c366
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
<原著>耳下腺アミラーゼ活性の周期性変化におよぼす急性ストレプトゾトシン糖尿病の作用について (614.6 kB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 1984-06-30 | |||||
| タイトル | ||||||
| タイトル | <原著>耳下腺アミラーゼ活性の周期性変化におよぼす急性ストレプトゾトシン糖尿病の作用について | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | <ORIGINAL ARTICLE>Effect of Acute Diabetes on Cyclical Change in Rat Parotid Amylase Activity | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Acute diabetes | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | streptozotocin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | insulin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | isoproterenol | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | parotid gland | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 言語 | ja | |||||
| 著者名(日) |
倉橋, 昌司
× 倉橋, 昌司× 中村, 治雄× 猪股, 孝四郎 |
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| 著者所属(日) | ||||||
| ja | ||||||
| 東日本学園大学歯学部口腔生理学講座 | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| Department of Oral Physiology, School of Dentistry, HIGASHI-NIPPON-GAKUEN UNIVERSITY | ||||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The effect of acute diabetes on isoproterenol-induced cyclical changes in parotid amylase activity was investigated in rats. Food was withheld after isoproterenol injection in order to eliminate the effect of mastication on parotid functions. In vehicle-injected control rats, a single intraperitoneal injection of isoproterenol (4mg/kg body weight) markedly decreased the parotid soluble protein content and amylase activity within 2 h. These parameters almost returned to the initial preinjected or more higher levels 24 h after the injection. Parotid weight of control rats increased from 2 h to 24 h after the injection. These changes observed in control rats are consistent with the initial amylase output from parotid glands and subsequently amylase synthesis and accumulation in parotid glands. Acute diabetes was produced 24 h after the intraveneous injection of streptozotocin (70mg/kg body weight). In streptozotocin-induced diabetic rats, the initial decreases in parotid soluble protein content and amylase activity after isoproterenol injection were smaller than in control rats, and the recoveries of these parameters were also more smaller in diabetic rats than in control rats. Parotid weight of diabetic rats did not change after the injection. Both responses of amylase output and synthesis to isoproterenol in parotid glands appear to be reduced in acute diabetic rats. Isoproterenol increased the plasma insulin level in control rats. The plasma insulin level in diabetic rats was markedly lower than that in control rats, and this level did not show any appreciable changes after isoproterenol injection. These results suggest that in isoproterenolinduced cyclical change in parotid amylase activity basal insulin secretion is necessary for the initial amylase output from parotid glands, and the stimulated insulin secretion is necessary for subsequent amylase synthesis and accumulation in parotid glands. | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN0008135X | |||||
| 書誌情報 |
ja : 東日本歯学雑誌 巻 3, 号 1, p. 11-19, 発行日 1984-06-30 |
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| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
