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<総説>線維素溶解現象の臨床的意義 : 血液凝固と線溶の動的平衡
https://hsuh.repo.nii.ac.jp/records/7161
https://hsuh.repo.nii.ac.jp/records/716180db9c5f-640a-45d1-99f7-14c7f5044f9e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
<総説>線維素溶解現象の臨床的意義 : 血液凝固と線溶の動的平衡 (357.0 kB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 1984-12-31 | |||||
| タイトル | ||||||
| タイトル | <総説>線維素溶解現象の臨床的意義 : 血液凝固と線溶の動的平衡 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | <REVIEW>Clinical Significance of the Fibrinolytic Mechanism : Dynamic Equivalent Mechanism between Blood Coagulation and Fibrinolysis | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Fibrinolysis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | plasminogen activator | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | fibrin I. | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 言語 | ja | |||||
| 著者名(日) |
安河内, 太郎
× 安河内, 太郎 |
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| 著者所属(日) | ||||||
| ja | ||||||
| 東日本学園大学歯学部内科学講座 | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| Department of Internal Medicine, School of Dentistry, HIGASHI-NIPPON-GAKUEN UNIVERSITY | ||||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Mammalian blood contains two opposite enzymatic systems. One is the coagulation system capable of clot formation of blood and the other is the fibrinolytic system capable of dissolving blood clots. Thrombus formation is brought about by the imbalance of the dynamic equivalent mechanism between blood coagulation and fibrinolysis. Fibrinolysis is known as the mechanism for dissolving of fibrin formed. It was, however, clarified by Nossel (1981) that the relative rate at which thrombin split the peptide of fibrin I, which was the fibrin of the first stage of the forming fibrin, and the relative rate at which plasmin split the peptide of fibrin I, could determine the occurrence of thrombosis. From this study it was proposed by Rosenberg & Rosenberg (1984) that the fibrinolytic system acts not only as the mechanism for dissolving of the fibrin formed, but also as one of the mechanisms for natural anticoagulation. The conversion of plasminogen to plasmin, which plays the main role in fibrinolysis, is due to the plasminogen activators. The plasminogen activators are classified as follows : One is the intrinsic plasminogen activators which are recognized in the blood obtained at rest. And the other is the extrinsic plasminogen activator mainly released from the endothelial cells of the vascular wall into the circulating blood by some mediators e. g. shock, stress, exercise, venous occlusion etc ……. It is speculated that the intrinsic plasminogen activator plays an important role as the natural anticoagulant mechanism of fibrinolysis, and that extrinsic plasminogen activator mainly acts as the mechanism capable of dissolving fibrin formed. In this paper are described outline of the new findings obtained regarding fibrinolysis, especially about the promoting factors and their function, and the clinical significance of fibrinolysis. | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN0008135X | |||||
| 書誌情報 |
ja : 東日本歯学雑誌 巻 3, 号 2, p. 139-144, 発行日 1984-12-31 |
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| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
