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実験的BLM肺線維症に関する放射線的研究
https://hsuh.repo.nii.ac.jp/records/7849
https://hsuh.repo.nii.ac.jp/records/7849595570b6-2fcc-41c6-887d-480faef14d16
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
実験的BLM肺線維症に関する放射線的研究 (4.0 MB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 1993-06-30 | |||||
| タイトル | ||||||
| タイトル | 実験的BLM肺線維症に関する放射線的研究 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | Experimental BLM Fibrosis of Lungs : Radiologic study | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 言語 | ja | |||||
| 記事種別(日) | ||||||
| ja | ||||||
| 原著 | ||||||
| 記事種別(英) | ||||||
| en | ||||||
| ORIGINAL ARTICLES | ||||||
| 著者名(日) |
前田, 静一
× 前田, 静一 |
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| 著者所属(日) | ||||||
| ja | ||||||
| 東日本学園大学歯学部 | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| Department of Dental Radiology, School of Dentistry, HIGASHI-NIPPON-GAKUEN UNIVERSITY | ||||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The process of experimental bleomycin (BLM) fibrosis of lungs was examined by means of lung scintigraphy in rats, and the agreement with histolgic or microangiographic features were evaluated. Rats were administrated 15mg/kg BLM 3 times a week, individually, and examinations were performed. Lung scintigraphy was taken after ^<99m>Tc labeled macroaggregated albumin (^<99m>Tc-MMA) was given in the vein and equilibrium was attained. Histologicaly, at 6 week after administration of BLM, collagen fiber formation was observed around vessels and bronchial tubes of the lungs and diaphragmatic pleura, and subsequently fibrosis progressed with the total ammount of BLM administered. The microangiographic findings, extension and/or stenosis of vessels was observed, and the capillary network was reduced, while decreased ^<99m>Tc-MMA uptake was observed as periferal lesions of the lungs in scintigram, especially at the bottom of the lungs. Both sets of findings were similar with the total ammount of BLM administration. In conclusion, it was suggested that the process of experimental. BLM fibrosis of lungs could be evaluated by lung scintigraphy in rats and that the findings would be parallel to histologic and microangiographic features. | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN0008135X | |||||
| 書誌情報 |
ja : 東日本歯学雑誌 巻 12, 号 1, p. 17-35, 発行日 1993-06-30 |
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| 出版タイプ | ||||||
| 出版タイプResource | VoR | |||||
