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ウサギ頭頂骨に設置したキャップ内の骨形成に対するPlatelet-rich Plasma影響
https://hsuh.repo.nii.ac.jp/records/8874
https://hsuh.repo.nii.ac.jp/records/8874944f153a-af1c-4007-afbf-da14b656aff3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ウサギ頭頂骨に設置したキャップ内の骨形成に対するPlatelet-rich Plasma影響 (1.6 MB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2004-06-01 | |||||
| タイトル | ||||||
| タイトル | ウサギ頭頂骨に設置したキャップ内の骨形成に対するPlatelet-rich Plasma影響 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | Effects of Platelet-rich Plasma on Bone Formation in a Cap placed on Rabbit Parietal Bone | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | PRP | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Rubbit | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Bone formation | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | β-TCP | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | GBR | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 言語 | ja | |||||
| 記事種別(日) | ||||||
| ja | ||||||
| 原著 | ||||||
| 記事種別(英) | ||||||
| en | ||||||
| ORIGINAL | ||||||
| 著者名(日) |
川田, 丈司
× 川田, 丈司× 廣瀬, 由紀人× 越智, 守生× 賀来, 亨× 矢嶋, 俊彦 |
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| 著者所属(日) | ||||||
| ja | ||||||
| 北海道医療大学歯学部歯科補綴学第二講座 | ||||||
| 著者所属(日) | ||||||
| ja | ||||||
| 北海道医療大学歯学部口腔病理学講座 | ||||||
| 著者所属(日) | ||||||
| ja | ||||||
| 北海道医療大学歯学部口腔解剖学第一講座 | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| Depatment of Fixed Prosthodontics School of Dentistry, Health Sciences University of Hokkaido | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| Depatment of Oral Pathology School of Dentistry, Health Sciences University of Hokkaido | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| First Department of Oral Anatomy School of Dentistry, Health Sciences University of Hokkaido | ||||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The aim of this study was to carry out a comparative assessment of the osteogenesis-promoting effects of platelet-rich plasma (PRP) in combination with different kinds of carrier compounds. An enclosed space was created by setting a cap on the rabbit parietal bone to study osteogenesis using the guided bone regeneration (GBR) method. The space was filled with PRP along with a bone-compensating carrier to induce osteogenesis, and the amount of osteoneogenesis in the cap was measured. First, various methods for collecting PRP were assessed. Then a pair of polypropylene caps were attached to the surface of the parietal bone of each rabbit. One of these caps was filled with one of the following carriers : Collagen, β-TCP, thrombin・β-TCP complex, or sodium alginate (control group); the other cap was filled with the same carrier soaked with PRP (experimental group). After8weeks, undecalcified samples were sectioned and used for histological observations and measurements of the amount of osteoneogenesis. In addition, longitudinal observations of osteogenesis guided by the β-TCP・PRP complex were carried out. The most suitable method for collecting PRP was found to be a double spin method (2400rpm for10min followed by 3600 rpm for 15 min), yielding a platelet concentration factor of 13.5. The amount of osteoneogenesis in the cap was higher in the experimental PRP (+) group than in the control PRP (-) group with any of the carriers tested. The amount of osteogenesis was greater in the β-TCP・PRP complex pair than in any of the other carrier pairs. In the longitudinal study of osteogenesis using the β-TCP・PRP complex, PRP was found to increase osteogenesis relatively early in the experiment. This experimental study supports the osteogenesis-promoting effects of the β-TCP・PRP complex with-out the combined use of thrombin, this suggests that the β-TCP・PRP complex alone will promote osteogenesis when used in clinical treatment. In addition, this method which uses no animal-derived thrombin, could have additional benefits in a clinical setting, preventing infection by unknown viruses or the side effects of abnormal blood coagulation. | |||||
| 言語 | en | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN0008135X | |||||
| 書誌情報 |
ja : 東日本歯学雑誌 巻 23, 号 1, p. 15-29, 発行日 2004-06 |
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| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
