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変形性関節症に関連する遺伝子多型についてのシステマティックレビュー
https://hsuh.repo.nii.ac.jp/records/9926
https://hsuh.repo.nii.ac.jp/records/992600df030c-b4c3-4be3-b9d7-23e29ca5dedd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
変形性関節症に関連する遺伝子多型についてのシステマティックレビュー (519.4 kB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-06-30 | |||||
| タイトル | ||||||
| タイトル | 変形性関節症に関連する遺伝子多型についてのシステマティックレビュー | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | Systematic review of polymorphisms related to osteorathritis | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Cytokine | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Polymorphism | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Osteoarthritis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Interleukin-1 (IL-1) | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Interleukin-1 receptor antagonist (IL-1RA) | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 言語 | ja | |||||
| 記事種別(日) | ||||||
| ja | ||||||
| システマティックレビュー | ||||||
| 記事種別(英) | ||||||
| en | ||||||
| Systematic review | ||||||
| 著者名(日) |
金澤, 香
× 金澤, 香× 柴田, 考典 |
|||||
| 著者名(英) |
KANAZAWA, Kaoru
× KANAZAWA, Kaoru× SHIBATA, Takanori |
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| 著者所属(日) | ||||||
| ja | ||||||
| 北海道医療大学歯学部口腔外科学第1講座 | ||||||
| 著者所属(日) | ||||||
| ja | ||||||
| 北海道医療大学歯学部口腔外科学第1講座 | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| First Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| First Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido | ||||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Osteoarthritis (OA) is the complex multifactorial disease of which the etiology is not yet well defined, and recently increasing attention has focused on the genetic risk factors of OA. The purpose of this study was to analyze the published literature on the association between genetic polymorphisms and OA by a systematic review method. Papers published from 1995 to March 2005 with the keywords cytokines, polymorphisms and OA, as well as papers among the references in these papers were obtained from Plumbed. The inclusion criteria were papers on the relationship between genetic polymorphisms of the Interleukin (IL)-1, 1L-1 receptor antagonist (RA), or the Tumor Necrosis Factor (TNF)-alpha and OA, and the paper includes retrospective studies that compare the prevalence of genetic polymorphisms of OA and healthy controls. Studies with fewer than ten subjects were excluded. Only three papers met the selection criteria, and these were reviewed. Evidence-based medicine data tables were drawn for each of the three papers respectively. There were significant differences (P=0.0007) in the frequencies of the T allele of IL-1β C3954T in the genetic polymorphism between OA patients with total hip or knee replacement and healthy controls. The evidence from the articles reviewed indicated a statistically significant correlation between OA and some specific polymorphisms of IL-1, but some of the reports showed bidirectional results. Further rigorous studies based on well-defined disease and control criteria will be required to contribute to the prevention and management of OA. | |||||
| 言語 | en | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA12060694 | |||||
| 書誌情報 |
ja : 北海道医療大学歯学雑誌 巻 24, 号 1, p. 99-104, 発行日 2005-06-30 |
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