WEKO3
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カルシウムシグナルと唾液分泌機能
https://hsuh.repo.nii.ac.jp/records/9912
https://hsuh.repo.nii.ac.jp/records/99123e212234-21f5-4ce0-8b7e-06dd1b08832c
名前 / ファイル | ライセンス | アクション |
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カルシウムシグナルと唾液分泌機能 (1.2 MB)
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
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公開日 | 2005-06-30 | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | カルシウムシグナルと唾液分泌機能 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Clcium signaling and salivary secretory function | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | カルシウムシグナル | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | 唾液腺 | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | 唾液分泌 | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | カルシウム蛍光指示薬 | |||||
キーワード | ||||||
言語 | ja | |||||
主題Scheme | Other | |||||
主題 | イメージング | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ページ属性 | ||||||
内容記述タイプ | Other | |||||
内容記述 | P(論文) | |||||
言語 | ja | |||||
記事種別(日) | ||||||
ja | ||||||
総設 | ||||||
記事種別(英) | ||||||
en | ||||||
REVIEW | ||||||
著者名(日) |
東城, 庸介
× 東城, 庸介 |
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著者名(英) |
Tojyo, Yosuke
× Tojyo, Yosuke |
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著者所属(日) | ||||||
ja | ||||||
北海道医療大学小児外科学部歯科薬理学講座 | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Dental Pharmacology, School of Dentistry, Health Sciences University of Hokkaido | ||||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Calcium ion (Ca^<2+>) plays an essential role as a second messenger in secretion of water and electrolytes in salivary glands. Many studies using fluorescent Ca^<2+> indicators such as quin-2 and fura-2 have shown that stimulation of muscarinic, α-adrenergic, or substance P receptors cause a rapid increase in [Ca^<2+>]_i in salivary gland cells resulting from the production of inositol 1,4,5-trisphosphate (IP_3). The [ra~<2+>]_i response is attributed to Ca^<2+> release from intracellular Ca^<2+> store followed by Ca^<2+> entry across the plasma membrane. The increase in [Ca^<2+>]_i is initiated in the apical pole of acinar cells and then rapidly spreads as a Ca^<2+> wave toward the basolateral region. The apical-to-basal pattern of Ca^<2+> signaling is probably important to activate the ion transport systems in salivary glands. In this review, I discuss mechanisms and physiological significance of the polarized Ca^<2+> signaling in salivary gland cells. | |||||
言語 | en | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12060694 | |||||
書誌情報 |
ja : 北海道医療大学歯学雑誌 巻 24, 号 1, p. 1-11, 発行日 2005-06-30 |