Item type |
紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) |
公開日 |
2000-12-30 |
タイトル |
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タイトル |
<原著>コーティング・ハイドロキシアパタイト顆粒の骨形成能に関する実験的研究 |
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言語 |
ja |
タイトル |
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タイトル |
<ORIGINAL REPORT>Experimental study of bone formation ability of coated hydroxyapatite particles |
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言語 |
en |
言語 |
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言語 |
jpn |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Hydroxyapatite |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Bone formation |
キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Mandibular bone |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
ページ属性 |
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内容記述タイプ |
Other |
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内容記述 |
P(論文) |
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言語 |
ja |
著者名(日) |
小田,浩範
柴田,敏之
村田,勝
有末,眞
村瀬,博文
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著者名(英) |
ODA,Hironori/SHIBATA,Toshiyuki/MURATA,Masaru/ARISUE,Makoto/MURASE,Hirofumi
WEKO
26038
en |
ODA,Hironori/SHIBATA,Toshiyuki/MURATA,Masaru/ARISUE,Makoto/MURASE,Hirofumi
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Search repository
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著者所属(日) |
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ja |
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北海道医療大学歯学部口腔外科学第二講座/北海道医療大学歯学部口腔外科学第二講座/北海道医療大学歯学部口腔外科学第二講座/北海道医療大学歯学部口腔外科学第二講座/聖路加国際病院口腔外科 |
著者所属(英) |
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en |
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Second Department of Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido/Second Department of Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido/Second Department of Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido/Second Department of Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido/Department of Oral and Maxillofacial Surgery, St. Luke's International Hospital |
抄録(英) |
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内容記述タイプ |
Other |
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内容記述 |
It is well known that hydroxyapatite (HAP), which has a high tissue affinity and superior bone conductivity, shows different characteristics depending on the sintering temperature. This study prepared single hydroxyapatite (SHAP) and coated hydroxyapatite (CHAP). The SHAP was sintered at high temperature (1250℃). The structure of CHAP was low temperature (150℃) sintered apatite coated with SHAP. The usefulness of CHAP for bone formation was examined in cylindrical bone defects (diameter : 5mm ; depth : 9mm) created in the mandible of adult dogs 2 months after extraction of the teeth (P4, M1). Calcein (8mg/kg) was injected 2 days before scarification and mandibular bone was removed at 7, 14, 30, 60, 90, and 120days. The explanted bone was fixed in 10% formaldehyde in saline and soaked in Villanueva bone stain solution. Non-demineralized coronal sections (70μm) were made and observed by fluorescence microscopy and microradiography. At 7days after implantation, bone formation occurred from the cavity surface in the CHAP group, but not in the SHAP group. At 14days, newly formed bone was observed around the HAP particles only in the CHAP group. Bone formation in the CHAP group was more rapid than in the SHAP group until 90days, though no significant differences were observed at 120days. These results suggest that CHAP particles may be useful as a filling material for bone defects in the field of oral and maxillofacial surgery. |
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言語 |
en |
雑誌書誌ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN0008135X |
書誌情報 |
ja : 東日本歯学雑誌
巻 19,
号 2,
p. 159-170,
発行日 2000-12-30
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