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酸素ラジカル発生系に及ぼす歯科用麻酔薬の影響
https://hsuh.repo.nii.ac.jp/records/8425
https://hsuh.repo.nii.ac.jp/records/842565910680-6e20-40aa-a67f-8360afadc21e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
酸素ラジカル発生系に及ぼす歯科用麻酔薬の影響 (1.7 MB)
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| Item type | 紀要論文(ELS) / Departmental Bulletin Paper(ELS)(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 1999-06-30 | |||||
| タイトル | ||||||
| タイトル | 酸素ラジカル発生系に及ぼす歯科用麻酔薬の影響 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | Influence of local anesthetics upon oxygen radical generation | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Local anesthetic | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | alkoxyl radical | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | hydroxyl radical | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | epinephrine | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ページ属性 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | P(論文) | |||||
| 言語 | ja | |||||
| 記事種別(日) | ||||||
| ja | ||||||
| 原著 | ||||||
| 記事種別(英) | ||||||
| en | ||||||
| ORIGINAL | ||||||
| 著者名(日) |
神田, 秀治
× 神田, 秀治 |
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| 著者所属(日) | ||||||
| ja | ||||||
| 北海道医療大学歯学部歯科放射線学講座 | ||||||
| 著者所属(英) | ||||||
| en | ||||||
| Department of Dental Radiology, school of Dentistry, Health Sciences University of Hokkaido | ||||||
| 抄録(英) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | This study examined whether local anesthetics react with superoxide (O・/2) radicals and generate other oxygen radicals. Lidocaine, mepibacaine, prilocaine, and dibucaine were used as amido type anesthetics ; procaine, and tetracaine as ester type anesthetics ; and epinephrine and ephedrine as epinephrine-like substances. A hypoxanthine-xanthine oxidase (HPX-XOD) reaction system was employed as the O・/2 generator. Detection and measurements were carried out with the ESR spin trapping method. When amido type anesthetics were added with epinephrine, alkoxyl (RO・) and hydroxyl (HO・) radical generation was confirmed, but there was no RO・ and HO・ generation with ephedrine. With ester type anesthetics with epinephrine, there was no RO・ generation. The signal intensities of RO・ and HO・ were dependent on the concentration of anesthetics and epinephrine. These results show that RO・ and HO・ generation by local anesthetics occur only where amido type anesthetics, cathecols, and (O・/2) are present. | |||||
| 言語 | en | |||||
| 雑誌書誌ID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN0008135X | |||||
| 書誌情報 |
ja : 東日本歯学雑誌 巻 18, 号 1, p. 117-140, 発行日 1999-06-30 |
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